mpMRI before biopsy does make sense!

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mpMRI before biopsy does make sense!

This prospective randomized multicenter trial shows the benefits of performing mpMRI of the prostate as a first step in the management of biopsy naïve patients with clinically suspected prostate cancer.

Kasivisvanathan V. and PRECISION Study Group Collaborators. MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis. N Engl J Med. 2018 Mar 18. doi: 10.1056/NEJMoa1801993. [Epub ahead of print] PubMed PMID: 29552975.

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PSA-Density: easily obtainable clinical parameter to help excluding significant prostate cancer.

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PSA-Density: easily obtainable clinical parameter to help excluding significant prostate cancer.

The study shows an increase in the NPV for exclusion of significant prostate cancer when PSA-Density is included as a parameter into the PIRADS-algorithm. 

Distler FA, Radtke JP, Bonekamp D, Kesch C, Schlemmer HP, Wieczorek K, Kirchner M, Pahernik S, Hohenfellner M, Hadaschik BA. The value of PSA density in combination with PI-RADS for the accuracy of prostate cancer prediction. J Urol. 2017 Mar 31. [Epub ahead of print] 

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